Mutation system questions

I've finally acquired primers and catalyst, but I have some questions. I play on experimental
How many primers and catalysts can I consume before OD on mutagen?
Can I become addicted to mutagenic catalyst?
If i just mutate one mutation branch, how many negative mutations will I get (or whats the chance to get negative one)?
How does Robust Genetics work now? How much does it negate chance to get negative mutation?