pulse-dosing of mood stabilizers in bipolar?
Has anyone tried pulse-dosing of mood stabilizers during the luteal phase for women with bipolar disorder who experience mood symptoms during this time?
I found a journal article that indicated SSRI use would be inappropriate in this population and that ultimately more randomized clinic trials are needed.
Hormonal agents are an option, but for a particular case I’m considering, multiple trials of different contraceptives have only led to worsening mood symptoms.
Wondering if anyone has utilized this in practice? Was it effective for symptom management?
I’ve not had any success in finding literature that specifically addresses pulse-dosing of mood stabilizers.