Bands that hate their big hit

I've heard or read many times that Radiohead hates "Creep" even though that's a the first song that comes to a lot of people's minds when they think Radiohead and it got tremendous radio play and covers.

Is this unusual, or do a lot of artists hate their big hit? I can imagine getting sick of playing shows and audiences only wanting to hear that one big song they heard on the radio and not knowing much else.

I'm seeing The Pixies tonight. How much of the audience is there for "Where is my Mind?" How many will be there to hear Modest Mouse play "Float On"?

I was thinking of this because I was recently at a CKY show and the audience kept screaming for "96 Quite Bitter Beings," as if that's their only song, but it's the closest thing CKY has ever had to a hit in 25 years.