Psilocybin Extraction Method

Typically, the process for extracting psilocybin from mushrooms involves making a solution that can dissolve the psilocybin, then separating the psilocybin from the other substances in the solution. Here is an outline of the general process.

Preparation: Dry the mushrooms and then grind them to a fine powder.

Extraction: Psilocybin can be extracted using a polar solvent like ethanol or methanol. Acidified water could also work, but the efficiency might be less. Mix the mushroom powder with your solvent and allow it to sit at room temperature. Psilocybin is heat sensitive and could degrade if exposed to high heat, so it's usually not necessary to heat the mixture.

Filtration: After sufficient time (typically hours), filter the mixture to remove the undissolved mushroom material.

Evaporation: If you're using a volatile solvent like ethanol or methanol, evaporate the solvent to leave behind the psilocybin. If you're using water, you may need to use a different method, such as freeze-drying.

Purification: The remaining product will likely still contain impurities. More sophisticated chemistry may be required to purify the product, such as chromatography.

Chromatography