Is Tokyo Station area a good base for our itinerary?

We're visiting Tokyo this summer, and I'm trying to figure out the best place to base ourselves.

Our itinerary includes:

• the area around SkyTree
• Senso-ji temple
• Shibuya
• Shinjuku
• Tokyo Disneyland / DisneySEA

What we're looking for:

• a safe area with a good amount of restaurants
• easy train access to (or within walking distance of) the places above
• easy to get to Tokyo Station to catch the Shinkansen to Kyoto for the next leg of the trip
• we're okay with a noisier area if it's super-convenient

I'm looking at the area east of the train station -- that seems to be centrally located to everything above, plus we can walk to the station on the last day with our luggage. But is Tokyo Station too massive to get around easily from there? i.e. are we better off basing ourselves in another area and/or near a smaller station?

Thanks in advance!