How should I deal with my parents not being supportive with my latest decision?

My parents have always been really supportive in my life through both difficult and happy times. This is something I wish could continue since we share a deep trust. I'm a 30 year old engineer who has had two jobs so far, but I have been thinking for quite some time about changing careers. I have also experienced a lot of loneliness and isolation along with many changes at my current job. I don't feel I am going to meet anyone by staying in the same seeing the same toxic people etc.

When I told them that I had recently been offered a place at a prestigious university in my country their reaction was not the same as the first time I started studying when I was 19. They did not really like the idea nor did they support it: I might only end up miserable, depressed, meet the wrong kinds of people etc. since I have to study very hard and spend time alone. I don't fully blame them as I think partly my parents don't understand my generation.

We have access to a lot of new things: like remote work and the ability to study anything. But if we stay in a place we don't like, we start to suffer mentally. Of course I am also not fully sure of what I want, but in worst case if I don't like my new place at university I can quit. I already have a degree so I can find a new job. I have already completed some courses so I am confident enough that I want to try this.

Secondly, I understand my parents are getting older and would appreciate if I was reachable a bit more. My mother has had some health issues in the past years and she is now better. It's just I wish they could still be supportive of my decision the same way they used to be when I was younger. I'm wondering how can I explain my view to them so they understand it better?