What are some of the most devastating lines from fantasy books?

"Children are dying." - Deadhouse Gates, Malazan Book of the Fallen.

I don't think I have come across a line more devastating and painful with its implications than this one from Malazan. It disturbs me by the cruelty of human existence, evil and ignorance.

What are some lines that have shook you to your core when you read it?

Edit: A little bit of light-spoiler context would be helpful.