Losing your youthful looks or your vitality as you grow old isn't the most painful part of it.
(76m) here. If you live long enough, the most searingly painful part of it by far isn't that your looks are gone or your body has broken down.
It's outliving the ones you've loved. The ones who loved you back.
Parents, sisters and brothers - wives and husbands - close friends. Outliving them means that you will be there to experience their death and to suffer and mourn their loss. For me, it is, without a doubt, the most tragic aspect of surviving into old age as well as the loneliest.
You never stop missing them once they're gone and you can't stop them from going.